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This medicine may well cause you to dizzy, drowsy, puzzled, or disoriented. Usually do not drive or do anything that may be risky until finally you know how this medication affects you.

Monitoring with resources such as the Opioid Possibility Software (ORT) assists recognize clients with a heightened danger for misuse. This Software helps to select which Continual soreness sufferers may get pleasure from other pain Manage modalities besides narcotics.

Codeine is actually a member of your opioid course of drugs which is employed to manage soreness. Codeine can be used to treat cough. For gentle-to-reasonable suffering, codeine is frequently used being a merged medication with acetaminophen or having an NSAID like ibuprofen. The drug is frequently out there as a combination item with promethazine or an NSAID like salicylic acid for cough and cold. Codeine is often marketed in the form of tablets and syrups. Although opioids are important agents for dealing with agony, Additionally they carry a high danger of misuse, abuse, dependancy, and increased mortality, as shown by The existing opioid epidemic and accompanying overdose deaths.

INDICATIONS AND USAGE Promethazine with Codeine Oral Answer is a combination of codeine, an opioid agonist; and promethazine, a phenothiazine, indicated to the temporary reduction of cough and higher respiratory indicators associated with allergy or the widespread cold in individuals eighteen yrs of age and more mature. (1)

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Box Warning: Pediatric people with obesity or disorders which can impair respiration, which includes These with a record of tonsillectomy or adenoidectomy.[22]

Codeine and hydrocodone may communicate with sedative medicines, Primarily benzodiazepines. Mixing these remedies can affect respiratory and might possibly be lethal. This mixture was chargeable for Nearly 14% of overdose deaths involving opioids in 2021.

If you're prescribed this medication on an everyday timetable and skip a dose, acquire it when you remember. Whether it is near the time of the following dose, skip the skipped dose. Acquire your future dose on the typical time. Never double the dose to capture up.

Go through the Medication Guide furnished by your pharmacist before you start taking promethazine/phenylephrine/codeine and every time you can get a refill. In case you have any queries, check with your health practitioner or pharmacist.

Physical dependence may well lead to withdrawal Negative effects if procedure is stopped out of the blue. On the other hand, significant withdrawal Unwanted effects can ordinarily be prevented by step by step lowering the dose about a length of time right before therapy is stopped fully.

Speak with your medical professional Should you have any questions on using codeine or about how this drugs could influence your child.

The concomitant use of opioids with other medication that affect the serotonergic neurotransmitter method has resulted in serotonin syndrome.

Promethazine shouldn't be employed by young children youthful than 2 decades because it may result in severe (perhaps lethal) slow/shallow respiration. This issue has Promethazine codeine syrup transpired Despite usual doses Within this age team.